Lemierre’s syndrome is a rare and in some cases fatal thrombophlebitis of the internal jugular vein (IJV). It usually follows acute oropharyngeal or otologic infections in healthy, young children. Fusobacterium necrophorum is the most common bacteria that causes Lemierre’s syndrome, whereas various microorganisms are reported. We report a case of Lemierre’s syndrome secondary to chronic otitis media, which remains a rare occurrence of a very seldam disease.