Investigation of Regenerative Effects of Theranekron® and Misoprostol after Partial Hepatectomy in Rats
Author(s):
İsmet Yılmaz1*, Burhan Hakan Kanat2, Azibe Yildiz3, Yilmaz Bilgiç4, Ahmet Berk5, Ayşe Burçin Uyumlu6
and Muhammet Burak Açikgül1
In the present study we were aimed to investigate/compare regenerative effects of Theranekron® (TC) and Misoprostol (MS) after Partial Hepatectomy (PH) in rats. This study was conducted in 38 rats, they were divided in to 5 groups and 7 days study periot. When considering biochemical and histopathological results; we were seen that after PH 7 days duration was not sufficient and also at least 10 days periot may be necessary. Althought some literatures were reported about positive effects of TC and MS on epithelial growing, we have not seen that they have not any positive effect on liver regeneration. In the future -at different doses and durations- these may be found effective.
