Post Burn Squamous Cell Carcinoma
Author(s):
Al-Daqaf Mohammad1* and Eman Al-Daqaf2
Introduction: Squamous cell carcinoma is the second most common skin cancer, ranking behind basal cell carcinoma. Its incidence is approximately 20–25% of that of basal cell carcinoma. Squamous cell cancer arising in injured areas have a high propensity for metastases and local recurrence.Treatment options for squamous cell carcinoma are generally divided into excisional therapies and superficial ablative therapies. Tumor location, size, depth of invasion, and histologic differentiation affect treatment choices. All patients with squamous cell cancer require close follow-up to monitor for local recurrence and metastases. The chance of developing a second skin cancer within 5 years after treatment of the original basal cell or squamous cell cancers as high as 50%.Objective• To assess the relation between the degree of the burn and skin squamous cell carcinoma cancer.• To assess the latent period between burn and the developed skin squamous cell carcinoma cancer.• To assess the incidence of metastasis from skin squamous cell carcinoma after burn, and the mostly site of metastasis.Materials and Methods: During the study period, fifty patients were targeted from 2200 burn patient who get skin cancer after burn. who were admitted to Al- Amal Oncology Center, Taiz, Yemen, between June 2014 and May 2017.Patients were eligible for inclusion (Any patient of any age and any gender, who had skin cancer after burn), for an descriptive cross-sectional. excluded based on the presence of synochronouse/ metachronous cancer.The statistical analysis was performed using SPSS (statistical package for social science), version 25.Data exhibited in figures and tables and summarized as percentages, frequencies, means and standard deviations.Results: 50 patients who have SCC from 2200 burn patients examined retrospectively. The number of SCC developing on burn scars among the 2200 burn cases was 50 (2.3%), The mean age was 45 ± 15.5 years, The highest percentage of patients ages was 50% and it was for the age group from 41 to 60 years. Forty-one of fifty SCCs cases with a percentage of 82% had suffered from third degree burns. Thirty of fifty SCCs cases with the percentage 60%, had 5- 10 years as latent Period between burn and carcinoma development. Twenty-nine of fifty SCCs cases with percentage of (58%) did not have metastasis, followed by 21 (42%) had a metastasis. And lung is the most common site of metastasis with about 10 (46%).
