Targeted Therapy in Management of Advanced Follicular Thyroid Carcinoma
Author(s):
Leong Tung Ong
Follicular thyroid carcinoma (FTC) is the second most common malignancy involving the thyroid glands. Early stages of FTC are managed with total thyroidectomy followed by 131I ablation and external beam radiation therapy. Targeted therapy with tyrosine kinase inhibitors (TKIs) is an essential therapeutic option for the management of advanced cases of radioactive iodine refractory. This review will investigate the clinical data for the therapeutic use of targeted therapy in advanced FTC and compare the efficacy of different targeted therapy used in managing the patients.