Transfusion Dependent Anemia, and Cytopenia Secondary to Parvovirus B19 Infection as the First Manifestation of X-linked Hyper IgM Immunodeficiency Syndrome in Two Male Patients in Their Third Decade of Life
Author(s):
Hadeel El-Haddad
We describe two male patients with unique mutation of CD40L gene, unlike classic presentation of X-linked hyper IgM immunodeficiency syndrome (XHIGM syndrome), both were healthy until presenting in their early twenties with a challenging symptomatic transfusion-dependent anemia, investigations confirmed XHIGM syndrome with concurrent chronic Parvovirus infection.
