Author(s): Marcelo Luis Pierro Saraiva, Marise Samama, Eduardo Carvalho de Arruda Veiga*, Fabio Ikeda, Rita de Cassio de Camargo Preto Piscopo, Jarmy-Di Bella S and Joji Ueno
ABSTRACT
Background: Letrozole is a medication that alone or combined with clomiphene citrate has been used for ovarian stimulation in women undergoing IVF. The objective of this narrative review is to investigate in the recent literature what are the main findings related to the use of letrozole in ovarian induction in human reproduction.
Methods: The search strategy was to use the keywords letrozole and ovarian stimulation and in vitro fertilization in the PubMed database in the last five years in free-text articles.
• Results-62 articles were found that applying the eligibility criteria were selected for this narrative review 12 articles.
• Results-The main findings of this study include information about the author, year, country, study design, number of participants, and more findings of each of the papers selected for this narrative review.
Conclusion: Although letrozole is a low-cost and safe medication for women, widely used in ovarian stimulation with benefits in endometrial receptivity, clinical results such as pregnancy rate and a number of live births still need large randomized trial studies.
