Author(s): <p>Firew Gemechu, Hagazi Tesfay, Haftom Temesegen and Meskelu Kidu*</p>
Introduction: Acute Kidney Injury (AKI) is the major cause of morbidity and mortality in hospitalized patients. Knowing the magnitude and outcome of AKI in patients admitted to ICU will help to increase awareness and prepare the resources required in improving care.
Objective: To examine the incidence and outcome of AKI in an intensive care unit in tertiary care hospital, in Tigray, Ethiopia.
Method: Prospective observational type of study was carried out to assess the incidence and outcome of AKI in a tertiary hospital from November 1 to April 1, 2020, G.C. Results: Of 152 patients admitted to the ICU during the study period 51.3% were males. The most common reasons for admission were the disease of the circulatory system (35%) and all forms of injury and poisoning (15.2%). The most common comorbidities were cardiac disease (41.6%), hypertension (25.7%), and diabetes mellitus (9.9%). Hemodialysis was given for 15.2% of patients and the mortality rate after hemodialysis was high around 85.7% and the overall mortality rate of patients with AKI was 56.5 %. The presence of anemia (AOR= 3.8 95%CI 1.8, 8.03), shock (AOR= 3.2 95%CI 1.5, 6.7), any focus of infection (AOR= 1.8 95%CI 0.8, 4.05) and liver function test derangement (AOR= 3.3 95%CI 1.5, 6.9) significantly affect the occurrence of AKI. Conclusion: The incidence of AKI was high in patients admitted to the ICU, and the development of AKI was associated with poor outcomes and reduced survival.
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